Applications

Let LigandTracer help you resolve your biological questions

LigandTracer is a highly flexible platform that allows you to perform a broad range of interaction studies. Simply immobilize one of the binding partners on a Petri dish (the target) and follow the binding of the labeled partner in solution (the ligand) in real-time. Here, we have summarized our main applications, based on what insights you are looking for or what kind of ligand or target you want to work with.

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Insights

Obtain new knowledge with LigandTracer

Quantify the kinetics and affinity of an interaction, or dig even further to explore details about the binding mechanism or follow cellular processes.

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Target

Target – the immbolized binding partner

The target is anything that can be attached to a Petri dish, such as a surface receptor of an adherent cell or an anchored suspension cell.

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Ligand

Ligand – the labeled binding partner in solution

The ligand is defined as the binding partner in solution. The most common ligand is a protein, but anything from a small synthetic compound to a large cell can be used as long as it can be labeled.

icon circle insights

Insights

Obtain new knowledge with LigandTracer

Quantify the kinetics and affinity of an interaction, or dig even further to explore details about the binding mechanism or follow cellular processes.

icon circle target

Target

Target – the immbolized binding partner

The target is anything that can be attached to a Petri dish, such as a surface receptor of an adherent cell or an anchored suspension cell.

icon circle ligand

Ligand

Ligand – the labeled binding partner in solution

The ligand is defined as the binding partner in solution. The most common ligand is a protein, but anything from a small synthetic compound to a large cell can be used as long as it can be labeled.

Applications with our instruments

The different instrument models vary in what type of label they detect (Green for fluorescence, Yellow, Grey and White for radionuclides), but all follow the same measurement principle. Therefore, most applications can be done with all instrument models, with a few exceptions. The color indications in the upper right corner show the model(s) that are suitable for a particular application.

Applications with our instruments

The different instrument models vary in what type of label they detect (Green for fluorescence, Yellow, Grey and White for radionuclides), but all follow the same measurement principle. Therefore, most applications can be done with all instrument models, with a few exceptions. The color indications in the upper right corner show the model(s) that are suitable for a particular application.

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From then to now

A continuous adaptation to meet new scientific demands

LigandTracer started as an instrument for detecting protein – cell interactions in real-time. This is still our main application, highly appreciated by many, but we continue to explore
new uses for LigandTracer and how we can meet the needs and wishes of our clients. Where we once thought that binding rates on cells are too complex to describe with numbers we now have a vast library of methods to quantify not only different binding modes, but also some cellular processes. The initial target group of nuclear medicine scientist expanded greatly when we introduced the fluorescence detecting LigandTracer Green and we now see
LigandTracer often being used in antibody development, immunologic research, nanoparticle characterization, among many.

As we are always improving our products, we are eager to learn about your research interest so that we can explore the possibilities to make it work. After all, an application only
becomes valuable if someone is using it.