icon flag ligand

Small molecules

Characterize interaction properties of small molecules

Investigate the binding of low molecular weight compounds, such as drugs, FDG and DNA bases. The label is a radioactive isotope (14C, 18F, etc.) replacing its non-radioactive counterpart during synthesis, which ensures that the interaction properties of the molecule are not affected.

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Cells

Key applications

Resources

Publications

[18F]FEPPA: Improved automated radiosynthesis, binding affinity and preliminary in vitro evaluation in colorectal cancer.
Berroterán-Infante N, Balber T, Fürlinger P, Bergmann M, Lanzenberger R, Hacker M, Mitterhauser M, Wadsak W.
ACS Med Chem Lett. 2018. 9(3):177-181.
PubMed

Effect of clofarabine on apoptosis and DNA synthesis in human epithelial colon cancer cells.
Wang X, Albertioni F.
Nucleosides Nucleotides Nucleic Acids. 2010. 29(4-6):414-418.
PubMed